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Author:
Okiemute Patricia Anyamaobi , Gloria N. Wokem, Ifeoma Bessie Enweani , Joan Nwamaka Okosa, AnasteciaIhuomaOkpe, Chidiebere Emmanuel Opara and Muodebe C Nwokeji
Antimicrobial properties of garlic (Allium sativum) and ginger (Zingiberofficinale) were investigated for their microbial activity against both clinical and laboratory isolates of Staphylococcus aureus using disc diffusion method. Ten isolates were obtained from the Department of Medical Microbiology, Medical Laboratory science Madonna University Teaching Hospital, Elele. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined by the broth dilution method. The antibiotic susceptibility test against the test organisms were performed by disc diffusion method. The result from this study showed garlic and ginger extract were effective against Staphylococcus aureus used in this study. The inhibitory effect exerted by garlic extract was highest at the concentration of 100µg/ml with mean zone inhibition of 11.5 ± 0.69mm which was statistically significant (p<0.05) from the control 21.6 ± 1.07mm. Also the inhibitory effect exerted by garlic was least at the concentration of 12.5µg/ml with mean zone of inhibition of 3.5 ± 0.46mm, while concentration at 50µg/ml showed mean zone of inhibition of 8.9 ± 1.11mm and concentration at 25µg/ml showed mean zone of inhibition of 5.6 ± 0.55mm. The inhibitory effect exerted by ginger was highest at the concentration of 100µg/ml with mean zone inhibition of 16.0 ± 0.21mm which was statistically significant (p<0.05) from the control 21.6 ± 1.07mm. Also the inhibitory effect exerted by ginger was least at the concentration of 12.5µg/ml with mean zone of inhibition of 4.5 ± 0.68mm, while concentration at 50µg/ml showed mean zone of inhibition of 11.7 ± 1.05mm and concentration at 25µg/ml showed mean zone of inhibition of 8.0 ± 0.89mm. Staphylococcus aureus was found to be more sensitive to ginger than garlic with highest mean zone inhibition of 16.0 ± 0.21mm for ginger and 11.5 ± 0.69mm for garlic at 100µg/ml. Also there were lower minimum inhibitory concentrations with 25µg/ml for garlic and 12.5µg/ml for ginger on Staphylococcus aureus than the minimum bactericidal concentrations with 50µg/ml for garlic and 25µg/ml for ginger indicating that the extracts could be bactericidal in action. Therefore garlic and ginger extracts can be used as a source of antibiotic substances for possible treatment of staphylococcal infection though not replacing the use of antibiotics but to prevent multidrug resistance.
Keywords:
Antimicrobial, Garlic, Ginger, Staphylococcus aureus, Elele, Nigeria
How to Cite this article:
Okiemute Patricia Anyamaobi et al.2020, Antimicrobial Effect of Garlic and Ginger on Staphylococcus Aureus from Clinical Specimens in Madonna University Teaching Hospital, Nigeria. Int J Recent Sci Res. 11(03), pp. 37840-37845.DOI: //dx.doi.org/10.24327/ijrsr.2020.1103.5189
DOI:
//dx.doi.org/10.24327/ijrsr.2020.1103.5189
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