February 04, 2015 Show
2 min read ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . We were unable to process your request. Please try again later. If you continue to have this issue please contact . Compared with Roux-en-Y gastric bypass, biliopancreatic diversion with duodenal switch resulted in greater weight loss and improvements in blood lipids and glucose 5 years after surgery, according to recent study findings published in JAMA Surgery. However, according to the researchers, patients who underwent duodenal switch experienced more long-term surgical and nutritional complications as well as more adverse gastrointestinal effects compared with those who underwent gastric bypass. Torsten Olbers, MD, PhD, of the department of gastrosurgical research and education, Sahlgrenska Academy at the University of Gothenburg in Sweden, and colleagues evaluated 60 adults aged 20 to 50 years with a BMI of 50 kg/m2 to 60 kg/m2 who underwent Roux-en-Y gastric bypass (n = 31) or biliopancreatic diversion with duodenal switch (n = 29) and compared the 5-year outcomes of each. After 5 years, BMI and weight reductions were greater among the duodenal switch group compared with the gastric bypass group (P < .001 for both). Similarly, total body weight loss was greater after 5 years for the duodenal switch group compared with the gastric bypass group (P < .001). Duodenal switch, but not gastric bypass, resulted in statistically significant decreases from baseline in total cholesterol, LDL cholesterol, diastolic blood pressure and mean fasting plasma glucose. Six patients who underwent duodenal switch and five in the gastric bypass group had type 2 diabetes before surgery; none used glucose-lowering medication 5 years after surgery, and remission was met by all patients who underwent duodenal switch. Compared with gastric bypass, duodenal switch yielded greater reductions in serum concentrations of vitamin A, 25-hydroxyvitamin D and ionized calcium, and a significant increase in parathyroid hormone. Gastrointestinal adverse effects were more common in the duodenal switch group. More surgical procedures related to the initial procedure and hospital admissions were found among patients who underwent duodenal switch. “In our study, duodenal switch resulted in greater weight loss and greater improvement in blood lipids and glucose compared with gastric bypass across 5 years in patients with baseline BMI of 50 to 60 [kg/m2],” the researchers wrote. “Improvement in [health-related quality of life] were comparable. However, duodenal switch was associated with more long-term surgical and nutritional complications and more gastrointestinal adverse effects compared with gastric bypass.” In an accompanying editorial, Justin B. Dimick, MD, MPH, and Oliver A. Varban, MD, both of the department of surgery at the University of Michigan, wrote that the high complication rates of duodenal switch reported in the study make that surgery difficult to recommend as a “first-line weight loss procedure.” “At the very least, patients seeking this procedure should receive ample warning regarding the very high risks of adverse nutritional outcomes and the high reoperation rate,” they wrote. “Patients with poor compliance and poor follow-up should not be offered this procedure because they could be at risk of fatal complications if postoperative problems are not addressed in a timely fashion.” Disclosure: Olbers reports financial ties with Johnson and Johnson. Dimick co-founded ArborMetrix. Please see the full study for a list of all other authors’ relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . We were unable to process your request. Please try again later. If you continue to have this issue please contact . Are you interested in bariatric surgery, and wondering if loop duodenal switch surgery (or SADI-S surgery) is right for you? The switch is the most powerful weight loss and type II diabetic treatment tool we have today. However, it’s not for everyone: after surgery, it requires that you adhere to a very strict vitamin and mineral regimen every day for the rest of your life to avoid malnutrition. It’s also a poor fit for some patients with certain health concerns. Use this checklist, complete with explanations, to decide if the duodenal switch is right for you compared to the gastric sleeve or gastric bypass. Is Your BMI > 50?Yes: SADI-S. It’s important to note that the SADI-S is still a viable tool for patients who don’t suffer from “super obesity.” But if you do need to lose more than 200 pounds to get down to your ideal weight, consider the switch. Do You Struggle with Irritable Bowel Syndrome?Yes: Gastric bypass or Sleeve. Do you have severe reflux?Yes: Gastric bypass. Duodenal Switch vs Gastric SleeveIs Your BMI > 50?Yes: SADI-S. SADI-S can help patients lose 80-100% of their excess weight, substantially more than the gastric sleeve. It is the most powerful (yet still safe) weight loss tool in modern medicine. Do You Have Type II Diabetes?Yes: SADI-S surgery (or gastric bypass). Do You Struggle with Inflammatory Bowel Disease or Chron’s Disease?Yes: Sleeve gastrectomy. Do You Suffer From Vitamin/Mineral Deficiencies?Yes: Sleeve gastrectomy. After SADI-S surgery, you’ll need to be extremely dedicated to taking vitamin supplements to avoid malnutrition, and even this may not be enough if you already suffer from baseline deficiencies. Comparatively, the sleeve gastrectomy doesn’t usually worsen vitamin and mineral deficiencies. So patients who suffer from deficiencies already can have the gastric sleeve without significant risk of worsening deficiency if they take recommended vitamins. If you have questions about baseline vitamin deficiencies, please call or send a message to our office today. Can You Consistently Commit to a Daily Vitamin and Protein Supplement Regime For Life?Yes: SADI-S can be safely
considered. SADI-S vs Lap Band SurgeryBecause of concerns about Lap Band complications and weight regain, we no longer perform Lap Band surgery at the BMCC. It is less safe and also less effective long-term than other bariatric surgeries. However, if you were considering Lap Band surgery, the SADI-S surgery may be right for you. Are You Considering SADI-S Surgery?This bariatric surgery is the most powerful and yet safe weight loss tool in modern medicine. However, it’s not for everyone. If you have certain pre-existing issues, or you cannot commit to a lifetime of strict vitamin and mineral supplements, then the switch may not be right for you. If that’s the case, you can learn more about the gastric bypass or sleeve gastrectomy, or just contact us today. But if your BMI is over 50 and/or you have type II diabetes, you don’t suffer from bowel issues or reflux, and you can commit to a lifetime of vitamin and protein supplements, then the SADI-S can be an extremely powerful weight loss tool for you. If you or a loved one has further questions or would like more information about the SADI-S surgery or other surgical or non-surgical weight loss solution, please check out our FREE ONLINE SEMINAR today. This page was medically reviewed by Dr. Joshua Long, MD, MBA, FACS, FASMBS. Dr. Long is a double-board-certified bariatric surgeon and bariatric medical director for Parker Adventist Hospital. What are the dangers of duodenal switch?Longer term risks and complications of a BPD/DS may include:. Bowel obstruction.. Dumping syndrome, causing diarrhea, nausea or vomiting.. Gallstones.. Hernias.. Low blood sugar (hypoglycemia). Malnutrition.. Stomach perforation.. Ulcers.. Is the duodenal switch worth it?Compared to other weight loss surgeries, duodenal switch cures the highest number of obesity-related health conditions (1). Patients who are not “cured” of their ailments typically experience dramatic improvements and an overall better quality of life.
How successful is duodenal switch?Duodenal switch surgery has a 90% success rate for weight loss. That means that 90% of people lose at least 50% of their excess weight. Most lose more. The surgery has a similar success rate for remission of related health conditions.
Which bariatric surgery is the most effective?The study found that gastric bypass appeared to be most effective for weight loss: Gastric bypass surgery resulted in an average 31 percent loss of total body weight in the first year and 25 percent of total body weight after five years.
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