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Human Anatomy6th EditionElizabeth Pennefather-O'Brien, Michael McKinley, Valerie O'Loughlin 1,592 solutions Human Anatomy and Physiology Laboratory Manual, Cat Version11th EditionElaine N. Marieb, Lori A. Smith, Susan J. Mitchell 176 solutions Answer Verified Hint: The process of digestion is done with the help of the digestive enzymes. The protein digestion starts in the stomach when the protein digesting enzyme pepsin activates. The HCL provides an acidic medium to activate several enzymes. The chief cells and parietal cells are present in the stomach. Complete answer: Hence, the correct answer is option (A). Note: The small amount of the pepsinogen is present in the serum of the healthy ruminants. The HCL secreted from the gastric glands is very essential for the digestion of the food. Most of the carbohydrate breakdown occurs in the mouth, with the help of the salivary amylase in the saliva. Protease helps in the breakdown of proteins while the lipase helps in the breakdown of fats. 1 The polymers in food are broken down into their constituent monomers by ____ reactions in the digestive tract. (p. 562) A) polymerization B) absorption C) condensation D) hydrolysis 2 The digestive system is specialized to perform all of the following functions except (p. 563) A) deglutition B) peristalsis C) metabolism D) defecation 3 Which of the following locations does not belong with the others? (p. 563) A) buccal cavity B) stomach C) salivary glands D) small intestine 4 Which of the following is not considered to be an accessory organ of the digestive system?(p. 563) A) teeth B) rectum C) pancreas D) gallbladder 5 Which of the following is a subdivision and does not belong with the other layers of the gastrointestinal wall? (p. 564) A) mucosa B) lamina propria C) submucosa D) serosa 6 Inner circular and outer longitudinal layers are characteristic of the ____ layer of the digestive tract. (p. 564) A) lamina propria B) muscularis mucosa C) submucosa D) muscularis externa 7 The outermost layer of the gastrointestinal tract is the (p. 565) A) muscularis mucosa B) muscularis externa C) serosa D) mucosa 8 Most of the digestive system receives its parasympathetic innervation from the (p. 565) A) vagus nerve B) thoracic spinal nerves C) lumbar spinal nerves D) sacral spinal nerves 9 Swallowed food first enters the ____ of the stomach. (p. 567) A) fundus B) corpus (body) C) cardiac region D) antrum 10 To enter the small intestine, partially digested food must pass through the (p. 567) A) gastroesophageal sphincter B) pyloric sphincter C) ileocecal valve D) sphincter of Oddi 11 Mucus is secreted throughout much of the alimentary canal by (p. 568) A) G cells B) enterochromaffin-like cells C) parietal cells D) goblet cells 12 Which of the following cell types does not belong with the others? (p. 568) A) alpha cells B) G cells C) enterochromaffin-like cells D) parietal cells 13 Pepsinogen is produced in the stomach by (p. 568) A) chief cells B) parietal cells C) enterochromaffin-like cells D) goblet cells 14 The hydrochloric acid secreted by the parietal cells of the stomach serves all of the following purposes, except (p. 569) A) the low pH produced by HCl makes pepsin more active B) the acid helps convert pepsinogen into pepsin C) it denatures dietary proteins and makes them more digestible D) it hydrolyzes the peptide bonds between the amino acids of dietary proteins 15 The most important function of the stomach, and perhaps the only function that appears to be essential for life is the (p. 568) A) digestion of carbohydrates B) digestion of proteins C) absorption of monosaccharides D) secretion of intrinsic factor 16 Contributing factors in acute gastritis include all of the following except (p. 571) A) regurgitation of bile salts from the duodenum into the stomach B) deficiency of bicarbonate C) hypersecretion of hydrochloric acid D) histamine secretion 17 The absorptive surface area of the small intestine is increased by all of the following except (p. 571) A) villi B) microvilli C) crypts of Lieberkühn D) plicae circulares 18 All of the following substances except ____ stimulate the secretion of gastric acid. (p. 587) A) epinephrine B) gastrin C) histamine D) acetylcholine 19 The longest part of the small intestine is the (p. 571) A) duodenum B) jejunum C) ileum D) cecum 20 More ____ is absorbed by the duodenum and the jejunum than by the ileum. (p. 571) A) vitamin B12 B) water C) carbohydrate D) bile salt 21 The lacteals of the small intestine are found in the (p. 571) A) Crypts of Lieberkühn B) central core of each villus C) submucosa D) each microvillus 22 The lacteals of the small intestine absorb (p. 573) A) monosaccharides B) amino acids C) electrolytes D) lipids 23 The term brush border refers to the ____ of the alimentary canal. (p. 573) A) plicae circulares B) rugae C) microvilli D) villi 24 Which of the following is a brush border enzyme? (p. 573) A) pepsin B) lactase C) trypsin D) amylase 25 A person typically drinks about 1,500 ml of water each day and takes in about 700 ml of water each day as moisture in food. The total amount of water received by the small intestine each day is, approximately (p. 577) A) 700 ml B) 1,500 ml C) 2,200 ml D) 8,000 ml 26 Lactose, salt, or other solutes that increase the osmolarity of the contents of the colon tend to cause (p. 577) A) diverticulitis B) acute gastritis C) diarrhea D) ulcerative colitis 27 The ____ prevent(s) feces from entering the anal canal when it is an inopportune time to defecate. (p. 577) A) haustra B) anal sphincters C) ileocecal valve D) diverticula 28 The bile contains all of the following components except (p. 580) A) lecithin B) albumin C) cholesterol D) urobilinogen 29 The liver performs all of the following functions except the (p. 581) A) synthesis of digestive enzymes B) conversion of glucose to fat C) phagocytosis of contaminating particles in the blood D) storage and release of glucose 30 The liver synthesizes all of the following except (p. 583) A) plasma albumin B) fibrinogen C) plasma globulins D) immunoglobulins 31 Urine and feces get their characteristic colors from which of the following pigments? (p. 581) A) urobilinogen B) free bilirubin C) conjugated bilirubin D) bile salts 32 Cholic acid and chenodeoxycholic acid are the main ____ in humans. (p. 581) A) bile salts B) bile pigments C) bile globulins D) conjugated bilirubin 33 A high rate of red blood cell destruction, with elevated levels of bilirubin in the blood, causes (p. 581) A) diverticulitis B) gallstones C) jaundice D) lithotripsy 34 The liver detoxifies ammonia by converting it to (p. 582) A) bilirubin B) urea C) uric acid D) nothing, since ammonia is processed by the kidneys and not the liver 35 The primary effect and purpose of hydroxylating steroid hormones in the liver is to (p. 583) A) raise their pH and prevent acidosis B) activate them so they can perform their hormonal functions C) make them less biologically active, more water soluble, and more easily excreted. D) incorporate them into micelles so they can be secreted into the bile. 36 The liver is able to make glucose from non-carbohydrates such as amino acids and fatty acids when the body's need for glucose is not met from dietary intake or glycogen reserves. This process is called (p. 583) A) glycogenesis B) glycogenolysis C) lipogenesis D) gluconeogenesis 37 Pancreatic juice does not include the following substance. (p. 585) A) insulin B) trypsin C) amylase D) bicarbonate 38 Many of the pancreatic enzymes must be activated by trypsin before they can begin digesting food, but trypsin itself requires the activating effect of (p. 585) A) chymotrypsin B) carboxypeptidase C) phospholipase D) enterokinase 39 The first hormone ever discovered was (p. 586) A) insulin B) secretin C) gastrin D) cholecystokinin 40 The smell, taste, or just the thought of food can activate gastric secretion and stomach motility by activating the (p. 587) A) sympathetic nervous system B) release of gastrin C) vagus nerve D) release of cholecystokinin (CCK) 41 The G cells of the stomach secrete gastrin in response to a couple of stimuli. One stimulus triggering gastrin release is the presence of (p. 588) A) fatty acids from lipids in the stomach chyme. B) the hormone somatostatin from the stomach D cells. C) short polypeptides and free amino acids in the chyme of the stomach. D) hydrochloric acid mixed with the stomach chyme. 42 Contraction of the gallbladder is stimulated by neural reflex as well as by the action of (p. 587) A) cholecystokinin (CCK) B) secretin C) guanylin D) somatostatin 43 The digestive enzyme that is most active at a pH of 2, is (p. 592) A) salivary amylase B) pancreatic amylase C) pepsin D) trypsin 44 More of the total daily calories in the average American diet come from the consumption of ____ than from any of these other components. (p. 592) A) lipids B) carbohydrates C) nucleic acids D) proteins 45 Three of the following are endopeptidases, with ____ as the only exopeptidase. (p. 593) A) trypsin B) elastase C) chymotrypsin D) carboxypeptidase 46 Each villus of the small intestine contains a lymphatic vessel called a lacteal which is specialized for the absorption of digested (p. 594) A) milk B) carbohydrate molecules C) protein molecules D) lipid molecules 47 The role of the enzyme, lipoprotein lipase is to (p. 594) A) emulsify dietary lipids so they can be digested more efficiently. B) remove triglycerides from chylomicrons in the blood. C) form micelles in the small intestine. D) digest lipids so they can be absorbed by the intestinal cells. Which cells contain pepsinogen?Pepsinogen is synthesized in the chief and mucous neck cells of the fundic region of the gastric mucosa and stored as secretory granules [95,96]. The stomach secretes stored pepsinogen in response to hormonal and neural stimuli [97].
Is pepsinogen secreted by Oxyntic cells?Pepsinogen is secreted from peptic (or chief) cells in the oxyntic gland. Some pepsinogen is also secreted from mucosal cells in the gastric antrum and the duodenum. In the presence of gastric acid this proenzyme is converted into active pepsin, which itself catalyzes further conversion from pepsinogen.
Where are pepsinogen producing cells found?Pepsinogens are synthesized and secreted primarily by the gastric chief cells of the human stomach before being converted into the proteolytic enzyme pepsin, which is crucial for digestive processes in the stomach.
How do chief cells secrete pepsinogen?Chief cells release the zymogen (enzyme precursor) pepsinogen when stimulated by a variety of factors including cholinergic activity from the vagus nerve and acidic condition in the stomach. Gastrin and secretin may also act as secretagogues.
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