What does the deoxyribonucleic acid refer to?

  • Your genome is made of a chemical called deoxyribonucleic acid, or DNA for short.
  • DNA contains four basic building blocks or ‘bases’: adenine (A), cytosine (C), guanine (G) and thymine (T).
  • The order, or sequence, of these bases form the instructions in the genome.
  • DNA is a two-stranded molecule.
  • DNA has a unique ‘double helix’ shape, like a twisted ladder.

What does the deoxyribonucleic acid refer to?

An illustration to show the double helix structure of DNA.
Image credit: Genome Research Limited

  • Each strand is composed of long sequences of the four bases, A, C, G and T.
  • The bases on one strand of the DNA molecule pair together with complementary bases on the opposite strand of DNA to form the ‘rungs’ of the DNA ‘ladder’.
  • The bases always pair together in the same way, A with T, C with G.
  • Each base pair is joined together by hydrogen bonds.
  • Each strand of DNA has a beginning and an end, called 5’ (five prime) and 3’ (three prime) respectively.
  • The two strands run in the opposite direction (antiparallel) to each other so that one runs 5’ to 3’ and one runs 3’ to 5’, they are called the sense strand and the antisense strand, respectively.
  • The strands are separated during DNA replication.
  • This double helix structure was first discovered by Francis Crick and James Watson with the help of Rosalind Franklin and Maurice Wilkins.
  • The human genome is made of 3.2 billion bases of DNA but other organisms have different genome sizes.

This page was last updated on 2022-02-18

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[ dee-ok-si-rahy-boh-noo-klee-ik, -nyoo-, -ok-si-rahy- ]

/ diˈɒk sɪˈraɪ boʊ nuˈkli ɪk, -nyu-, -ˌɒk sɪˌraɪ- /

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Definition of deoxyribonucleic acid

noun Genetics.

QUIZ

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Words nearby deoxyribonucleic acid

deoxygenate, deoxygenize, deoxyhemoglobin, deoxymannose, deoxyribonuclease, deoxyribonucleic acid, deoxyribonucleoprotein, deoxyribonucleoside, deoxyribonucleotide, deoxyribose, dep.

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2022

MORE ABOUT DEOXYRIBONUCLEIC ACID

What is deoxyribonucleic acid?

Deoxyribonucleic acid—better known by the abbreviation DNA—is a large, complex molecule that allows cells to function and carries the genetic code that determines the traits of a living organism.

DNA is in every cell of every living thing. Some viruses also have DNA.

Life as we know it wouldn’t exist without DNA—it contains the instructions that cells need to function. DNA is found in the cell nucleus, and every cell in an organism has the exact same copy of DNA that is in every other cell. Each cell uses its copy of DNA whenever it needs to make a protein. Proteins have many essential jobs within a living thing. For example, your immune system produces proteins called antibodies to fight germs.

The information that’s in DNA controls the development of specific traits, such as the shape of a leaf or the color of hair. Specifically, such traits are determined by genes, which are segments of DNA within strands called chromosomes. The set of all information contained in the DNA of any living thing—all of its inheritable traits—is called its genome.

Technically speaking, deoxyribonucleic acid is a type of macromolecule (a very large molecule—one composed of hundreds of thousands of atoms) known as a nucleic acid. Nucleic acids are made of smaller molecules known as nucleotides, which are made of a phosphate, a sugar, and nitrogen bases. The four nitrogen bases in DNA are adenine (A), thymine (T), guanine (G), and cytosine (C).

DNA has a shape known as a double helix, which resembles a spiraled ladder. The DNA ladder is built from two very long strands of nucleotides with the nitrogen bases pairing together to form the rungs of the ladder. The bases form base pairs, with adenine always paired to thymine and guanine always paired to cytosine. The phosphate and sugar within the nucleotide act as the sides of the ladder.

Because DNA only exists within the cell’s nucleus, the genetic information must be distributed somehow. This is one of the roles of RNA (ribonucleic acid), which is a macromolecule that works alongside DNA to make proteins. During this process, RNA acts as a kind of copy of the DNA that carries its genetic information outside of the cell nucleus.

We took a microscopic look at the differences between DNA, RNA, and mRNA, and their vital roles. Read all about it here!

Why is deoxyribonucleic acid important?

Deoxyribonucleic acid is ancient, but its discovery was relatively recent. In 1869, chemist Friedrich Miescher documented a kind of molecule that had never been studied before—nucleic acid. It wasn’t until around the 1930s that the terms deoxyribonucleic acid and DNA began to be used. In the 1950s, the work of biophysicist Rosalind Franklin and biologists James Watson and Francis Crick revealed DNA’s double helix structure.

Cells cannot make proteins without DNA. DNA acts as a set of instructions for any protein that needs to be made.

The study of DNA is central to the field of science known as genetics. DNA contains genetic information that is passed down from one generation to another. You get roughly half of your DNA from your mother and half from your father. This is the reason children look similar but not identical to their parents.

Despite the vast range of different physical traits that people can have, the DNA of all humans is more than 99% identical. Human DNA is made of billions of nitrogen bases, and even minor differences can result in two people that look very different. (Identical twins are born with the exact same DNA.)

The order of nitrogen base pairs is what makes every person and every living thing unique. For example, minor differences in this sequence determine whether a person will have brown eyes or blue eyes.

Did you know ... ?

Deoxyribonucleic acid is analyzed in the study of human evolution. Our closest living biological relatives are chimpanzees and bonobos, whose DNA is over 98% identical to ours. This fact has contributed to the theory that humans and chimpanzees share a common ancestor that lived millions of years ago.

What are real-life examples of deoxyribonucleic acid?

This illustration shows a simplified rendition of the double helix structure of deoxyribonucleic acid.

What does the deoxyribonucleic acid refer to?

Getty. DNA double helix.

Deoxyribonucleic acid is crucial to life, and learning about it is a crucial part of the study of biology.

Overheard a kid tell another kid how this looked like deoxyribonucleic acid at the park today and it made my little science teacher heart sing 💕🧬 pic.twitter.com/htQwVgz5jz

— McKenna Serowka (@mckenna_serowka) November 3, 2020

Today we had over 40 students (grade K-5) join us to learn how how to make deoxyribonucleic acid (DNA) models. @DrJeanita showed our learners how to transform their sweet treats into double helixes based on different sequences. Stay tuned to see our activities for next week! pic.twitter.com/CDgezx39PT

— STEAM FORWARD! Academy (@steam_forward_) January 30, 2021

Quiz yourself!

True or False?

Deoxyribonucleic acid is essential to life because it contains instructions for the production of proteins.

How to use deoxyribonucleic acid in a sentence

  • I write the lyrics and work with Murv Douglas from Lords of Acid.

  • During the height of his disenchantment, he visited his hometown where an old friend gave him some liquid acid.

  • Eggs, he says, are a good source of cysteine, an amino acid that helps the liver break down alcohol faster.

  • This at-home blood test kit gives a full reading of antioxidant, fatty acid, or vitamin panels.

  • The recent spate of acid attacks on women is only the latest manifestation of this dangerous trend.

  • There are a number of bacilli, called acid-fast bacilli, which stain in the same way as the tubercle bacillus.

  • The amount of the other purin bodies together is about one-tenth that of uric acid.

  • Uric acid is decreased before an attack of gout and increased afterward, but its etiologic relation is still uncertain.

  • An increase is also noted in the uric-acid diathesis and in diseases accompanied by respiratory insufficiency.

  • Indol is absorbed and oxidized into indoxyl, which combines with potassium and sulphuric acid and is thus excreted.

British Dictionary definitions for deoxyribonucleic acid

deoxyribonucleic acid

desoxyribonucleic acid

/ (diːˌɒksɪˌraɪbəʊnjuːˈkleɪɪk) /


noun

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for deoxyribonucleic acid

deoxyribonucleic acid

[ dē-ŏk′sē-rī′bō-nōō-klēĭk ]


The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

What is an example of a deoxyribonucleic acid?

DNA outside the nucleus is referred to as extranuclear DNA. Examples of extranuclear DNAs are mitochondrial DNA (mtDNA) and chloroplast DNA (cpDNA). The presence of nucleic acids in these organelles enables them to become semi-autonomous, self-reproducing organelles.

What is deoxyribonucleic acid quizlet?

DNA. DNA (definition) Deoxyribonucleic Acid; A nucleic acid found in the nucleus of all living cells, which carries the organism's hereditary information.

What is deoxyribonucleic acid made of?

DNA is a linear molecule composed of four types of smaller chemical molecules called nucleotide bases: adenine (A), cytosine (C), guanine (G), and thymine (T). The order of these bases is called the DNA sequence.