Describe the chemistry of buffer mechanisms and explain their relevant roles in the body A buffer is a solution which consists of a weak acid and its conjugate base, that can resist a change in pH when a stronger acid or base is added. Buffering:
Efficacy of a buffer system is determined by:
Buffer SystemsImportant buffer systems include:
All buffer systems are in equilibrium with the same amount of H+. This is known as the isohydric principle. Bicarbonate Buffer SystemThe bicarbonate buffer system is:
Hydrogen ions are consumed or released by the following reaction:
Bicarbonate is an effective buffer because it is:
Protein Buffer System
Haemoglobin Buffer SystemHaemoglobin is:
In the cell:
Phosphate Buffer SystemPhosphoric acid is:
References
results matching ""No results matching ""What is a common buffer in our blood?Human blood contains a buffer of carbonic acid (H2CO3) and bicarbonate anion (HCO3-) in order to maintain blood pH between 7.35 and 7.45, as a value higher than 7.8 or lower than 6.8 can lead to death.
What is the most important buffer in red blood cells?Hemoglobin is the major buffer system in the red cell. Its buffer power is strengthen through the Haldane effect.
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