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Organizational Behavior: Managing People and Organizations13th EditionJean Phillips, Ricky W. Griffin, Stanley Gully 174 solutions $\begingroup$ If I place a RBC in 0.5M urea we see haemolysis. My textbook says that "the solution is hypotonic. Urea enters the RBC down it's concentration gradient. Water follows the movement of urea by osmosis. This influx of water causes lysis". I am very confused by this, for a number of reasons.
I feel like I have a conceptual failing here, but the more I google the more confused I get.
AliceD♦ 51.6k18 gold badges169 silver badges236 bronze badges asked Feb 22, 2019 at 7:03
$\endgroup$ 1 $\begingroup$ I think you have the conceptual understanding down, but my guess is that the textbook is not representing the situation quite correctly. Based on the phrasing of the statement, I can imagine they are describing one of two situations:
Imagine a third situation now in which a RBC is at equilibrium with a solution. If you just added urea to the solution, it would not affect osmolarity in the long term for the reason you describe.
canadianer 17.5k4 gold badges48 silver badges84 bronze badges answered Feb 22, 2019 at 13:52
$\endgroup$ Is urea a penetrating solute in plants?Urea will cross into the cell, so it is a penetrating solute.
What is a penetrating solute?Penetrating solutes: solutes that can pass through a membrane. Non-penetrating solutes: solutes that cannot pass through a membrane.
Why does urea cause cell lysis?The consequence of this is that the effective osmotic pressure of a urea solution is lower than that of NaCl of the same osmolarity, and, as a result, the osmotic gradient across the cell membrane is increased, and water moves into the red blood cells via osmosis, causing the cell membrane to rupture and the cell to ...
Which of the following is an example of a penetrating solute?2. penetrating solutes-readily diffuse (i.e: urea). urea enters cells through aquaporins, which is the same way that H2O enters the cells. glucose can also be penetrating.
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