What would happen to a persons red blood cells if a solution containing 5% salt instead of the isotonic 0.9% salt were given intravenously?

Introduction
Osmosis is the physo-chemical process resulted from pressure differences.

Example of this principle is found on physiology on the celebrated Fick's law. Further, cells in general use this physical phenomenon for transporting important molecules in and out of the cells in what is named passive transport, no energy is demanded, no proteins is used for the job.

In the scheme below, mass will go from the high concentration side, left, to low concentration, right. It will go on until the concentrations will meet.

What would happen to a persons red blood cells if a solution containing 5% salt instead of the isotonic 0.9% salt were given intravenously?

Discussions

Blood cells are composed mainly of water, it will make up the proportion of about 90% of water for whole body. One nice example is when we remain too much time in the pool or sea water, our skin will change its normal state.

Because of the difference in osmotic potential caused by the salt water solution, water will diffuse out of the red blood cells causing them to shrink in size. Accordingly, this principle is used in the curing(*) of meat and vegetables; most of the bacteria will have their cells destroyed due the "water-stealing process."

Therefore, when we place blood red cells within a salty solution, pressure generated by concentration differences, of salt, higher outside, will make salt come in, due to cell-self protection mechanisms, not too much, and water will come out, eventually the cell can "crack." It can be seen for instance when a frog gets in touch with salt by the skin, they loose the skin-need humidity. On the upcoming picture, we have an schematic picture of a shrivelled cell.

Picture 1 Shrivelled cells, accessed on 11 02 2016

Notes.
(*) Curing is the addition to meats of some combination of salt, sugar, nitrite and/or nitrate for the purposes of preservation, flavor and color. http://nchfp.uga.edu/publications/nchfp/lit_rev/cure_smoke_cure.html. accessed on 10 02 2016.

Blood Laboratory

Red cell fragility > Osmotic hemolysis
  Cell membranes are semipermeable barriers, and osmotic gradients are established between intracellular and extracellular fluids which can cause water to flow into and out of the cells. The amount of osmotic pressure depends upon the difference between the concentration of non-diffusible ions on each side of the membrane.
The theoretical background for this exercise is to be reviewed in your text book.
The intracellular fluid of erythrocytes is a solution of salts, glucose, protein and hemoglobin. A 0.9% NaCl solution is said to be isotonic: when blood cells reside in such a medium, the intracellular and extracellular fluids are in osmotic equilibrium across the cell membrane, and there is no net influx or efflux of water.

When subjected to hypertonic media (e.g. 1.8% NaCl), the cells lose their normal biconcave shape, undergoing collapse (leading to crenation) due to the rapid osmotic efflux of water.

On the other hand, in a hypotonic environment (e.g. 0.4% NaCl or distilled water), an influx of water occurs: the cells swell, the integrity of their membranes is disrupted, allowing the escape of their hemoglobin (hemolysis) which dissolves in the external medium.

What would happen to a persons red blood cells if a solution containing 5% salt instead of the isotonic 0.9% salt were given intravenously?
Crenation

What would happen to a persons red blood cells if a solution containing 5% salt instead of the isotonic 0.9% salt were given intravenously?
Hemolysis

In this experiment, we make use of the property that the osmotic fragility (or susceptibility to hemolysis) of erythrocytes is not uniform, and the number of cells undergoing hemolysis depends on the degree of hypotonicity of the extracellular medium. The concentration of liberated hemoglobin in each test medium is an index of the extent of osmotic hemolysis. Your task is to examine the relationship between extent of hemolysis and osmolarity of the medium in which the erythrocytes are suspended.

To continue with the procedure of erythrocyte fragility, click here

   
 
 
 
 
 
   
 
 
   
 
 
 

What happens to red blood cells when placed in a 5% salt solution?

The cell will shrink as it loses water to the salt solution. The cell will resist osmosis due to its non permeable membrane.

What happens when red blood cells are placed in 0.9% NaCl solution?

The red blood cell has its normal volume in isotonic NaCl. Erythrocytes remain intact in NaCl 0.9%, resulting in an opaque suspension. Distilled water on the other hand is hypotonic to red blood cells.

What will happen to a red blood cell placed in a solution of 0.7 percent salt?

Since the concentration of the solution (0.7% salt) is lower than that of the cell (0.9%), water will move into the cell by osmosis to dilute the red blood cell concentration, and so the cell will swell up and maybe even burst.

What would happen to red blood cells placed in an isotonic solution?

When a red blood cell is placed in an isotonic solution, there will be no net movement of water. Both the concentration of solute and water are equal both intracellularly and extracellularly; therefore, there will be no net movement of water towards the solution or the cell.